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I'm developing an application in python that obtains some data from some other data container, and then it is supposed to set up and run the calculation  of an LCA model using openLCA as the calculation engine, and show the resultis in a custom-made graphical interface.

I want the user to be able to manipulate open LCA actions from the custom made interface with simplified buttons from the custom user interface to perform simple modelling tasks, using openLCA as a background-running calculation engine.

I don't want the user to have to open the openLCA GUI and perform configurations from within (like starting the ipc server).

Is there anyway I can achieve this?

Thanks in advance!
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Sure, this is possible, we do this but there are meanwhile also quite some other applications in use (via openLCA's Java API or gRPC API, https://github.com/GreenDelta/openLCA-ApiDoc).