when you create a new database in openLCA, does it appear on your external drive? And can you work with it normally?
Did you move all your databases or only a selection?
If the connection is not slow, putting databases on a different, also external location works. As a workaround, you could create a backup database from your "old" database (in the old location), which creates the zolca file (using the old / default ini settings), then change the ini to the new location on the external disc, and restore the database there.