In openLCA2 you can simply click "Regionalised calculation" to get elementary flows with their corresponding location in the results, which makes an extra "regionalised" version of a database kind of obsolete and you can use Cutoff, Consequential or APOS (without the extra regionalised version). For the impact assessment in openLCA2, you can easily add as many regionalised characterisation factors as you wish for each unique elementary flow, without the need for a "new" flow for each location. You can add or copy/paste the unique flow inside the characterization factors table and change the factor and the location.